Development and validation of a novel detection method for Rickettsia rickettsii using a loop-mediated isothermal amplification assay

Development and validation of a novel detection method for Rickettsia rickettsii using a loop-mediated isothermal amplification assay

IntroductionRickettsia rickettsii is an obligate, intracellular pathogen and the causative agent of Rocky Mountain spotted fever (RMSF). RMSF is an important zoonotic disease due to its high fatal outcome in humans. The difficulty of clinical diagnosis due to the low sensitivity and specificity of c...

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Bibliographic Details
Main Authors: Bertha I. Carvajal-Gamez, Aída Olguín-Barrera, Luis Tinoco-Gracia, Guadalupe Gordillo-Perez, Karla Dzul-Rosado, Gabriela Aguilar-Tipacamú, Mario Hidalgo-Ruiz, Juan Mosqueda
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Microbiology
Subjects:
Rocky Mountain spotted fever
diagnostics
tick-borne pathogens
isothermal amplification
Rickettsia
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1276809/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1276809/full

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