<it>M. leprae </it>inhibits apoptosis in THP-1 cells by downregulation of Bad and Bak and upregulation of Mcl-1 gene expression
<p>Abstract</p> <p>Background</p> <p>Virulent <it>Mycobacterium leprae </it>interfere with host defense mechanisms such as cytokine activation and apoptosis. The mitochondrial pathway of apoptosis is regulated by the Bcl-2 family of proteins. Expression of F...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-09-01
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| Series: | BMC Microbiology |
| Online Access: | http://www.biomedcentral.com/1471-2180/6/78 |