Sensitive screening of single nucleotide polymorphisms in cell free DNA for diagnosis of gestational tumours

Sensitive screening of single nucleotide polymorphisms in cell free DNA for diagnosis of gestational tumours

Abstract Tumours expressing human chorionic gonadotropin (hCG), the majority of which are difficult to biopsy due to their vascularity, have disparate prognoses depending on their origin. As optimal management relies on accurate diagnosis, we aimed to develop a sensitive cell free DNA (cfDNA) assay...

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Bibliographic Details
Main Authors: Geoffrey J. Maher, Rosemary A. Fisher, Baljeet Kaur, Xianne Aguiar, Preetha Aravind, Natashia Cedeno, James Clark, Debbie Damon, Ehsan Ghorani, Adam Januszewski, Foteini Kalofonou, Ravindhi Murphy, Rajat Roy, Naveed Sarwar, Mark R. Openshaw, Michael J. Seckl
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:npj Genomic Medicine
Online Access:https://doi.org/10.1038/s41525-022-00297-x

Internet

https://doi.org/10.1038/s41525-022-00297-x

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