2034 Effect of balanced crystalloids on renal outcomes among critically ill adults does not differ from 0.9% saline across baseline risk of renal outcomes

OBJECTIVES/SPECIFIC AIMS: Traditional clinical trials typically enroll a homogenous population to test the efficacy of an intervention. Pragmatic trials deliberately enroll a more diverse population to enhance generalizability, but doing so may increase heterogeneity of treatment effect among subpop...

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Bibliographic Details
Main Authors: Andrew C. McKown, Todd W. Rice, Matthew W. Semler
Format: Article
Language:English
Published: Cambridge University Press 2018-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866118001656/type/journal_article