Overexpression of REST Represses the Epithelial–Mesenchymal Transition Process and Decreases the Aggressiveness of Prostate Cancer Cells
The RE-1 silencing transcription factor (REST) is a repressor factor related to neuroendocrine prostate cancer (PCa) (NEPC), a poor prognostic stage mainly associated with castration-resistant PCa (CRPC). NEPC is associated with cell transdifferentiation and the epithelial–mesenchymal transition (EM...
Main Authors: | Sebastián Indo, Octavio Orellana-Serradell, María José Torres, Enrique A. Castellón, Héctor R. Contreras |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-03-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/25/6/3332 |
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