Epithelial senescence in idiopathic pulmonary fibrosis is propagated by small extracellular vesicles

Epithelial senescence in idiopathic pulmonary fibrosis is propagated by small extracellular vesicles

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects 3 million people worldwide. Senescence and small extracellular vesicles (sEVs) have been implicated in the pathogenesis of IPF, although how sEVs promote disease remains unclear. Here, we profile sEVs from...

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Bibliographic Details
Main Authors: Sabha Asghar, Susan Monkley, David J. F. Smith, Richard J. Hewitt, Ken Grime, Lynne A. Murray, Catherine L. Overed-Sayer, Philip L. Molyneaux
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Respiratory Research
Subjects:
Small extracellular vesicles
Exosomes
miRNA
Senescence
Idiopathic pulmonary fibrosis
Online Access:https://doi.org/10.1186/s12931-023-02333-5

Internet

https://doi.org/10.1186/s12931-023-02333-5

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