Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells
The differentiation of naive CD8 T cells into effector cytotoxic T lymphocytes upon antigen stimulation is necessary for successful antiviral, and antitumor immune responses. Here, using a mouse model, we describe a dual role for the let-7 microRNAs in the regulation of CD8 T cell responses, where m...
Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
eLife Sciences Publications Ltd
2017-07-01
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Colecção: | eLife |
Assuntos: | |
Acesso em linha: | https://elifesciences.org/articles/26398 |