Upregulation of Sarcolemmal Hemichannels and Inflammatory Transcripts with Neuromuscular Junction Instability during Lower Limb Unloading in Humans

Upregulation of Sarcolemmal Hemichannels and Inflammatory Transcripts with Neuromuscular Junction Instability during Lower Limb Unloading in Humans

Human skeletal muscle atrophy and a disproportionate force loss occur within a few days of unloading in space and on Earth, but the underlying mechanisms are not fully understood. Disruption of neuromuscular junction homeostasis has been proposed as one of the possible causes. Here, we investigated...

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Bibliographic Details
Main Authors: Giuseppe Sirago, Julián Candia, Martino V. Franchi, Fabio Sarto, Elena Monti, Luana Toniolo, Carlo Reggiani, Emiliana Giacomello, Sandra Zampieri, Lisa M. Hartnell, Giuseppe De Vito, Marco Sandri, Luigi Ferrucci, Marco V. Narici
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biology
Subjects:
disuse
hemichannels
inflammation
Online Access:https://www.mdpi.com/2079-7737/12/3/431

Internet

https://www.mdpi.com/2079-7737/12/3/431

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