Transplantation of Neural Precursors Derived from Induced Pluripotent Cells Preserve Perineuronal Nets and Stimulate Neural Plasticity in ALS Rats

Transplantation of Neural Precursors Derived from Induced Pluripotent Cells Preserve Perineuronal Nets and Stimulate Neural Plasticity in ALS Rats

A promising therapeutic strategy for amyotrophic lateral sclerosis (ALS) treatment is stem cell therapy. Neural progenitors derived from induced pluripotent cells (NP-iPS) might rescue or replace dying motoneurons (MNs). However, the mechanisms responsible for the beneficial effect are not fully und...

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Bibliographic Details
Main Authors: Serhiy Forostyak, Oksana Forostyak, Jessica C. F. Kwok, Nataliya Romanyuk, Monika Rehorova, Jan Kriska, Govindan Dayanithi, Ruma Raha-Chowdhury, Pavla Jendelova, Miroslava Anderova, James W. Fawcett, Eva Sykova
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
proteoglycans
plasticity
neurodegeneration
stem cells
iPS
ALS
Online Access:https://www.mdpi.com/1422-0067/21/24/9593

Internet

https://www.mdpi.com/1422-0067/21/24/9593

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