14-Substituted Diquinothiazines as a New Group of Anticancer Agents

14-Substituted Diquinothiazines as a New Group of Anticancer Agents

A series of novel double-angularly condensed diquinothiazines with aminoalkyl, amidoalkyl, sulfonamidoalkyl, and substituted phenyl groups was designed, synthesized, and evaluated for their anticancer activity against four selected human tumor cell lines (HTC116, SH-SY5Y, A549, and H1299). The cytot...

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Bibliographic Details
Main Authors: Małgorzata Jeleń, Krystian Pluta, Małgorzata Szmielew, Beata Morak-Młodawska, Kinga Herman, Klaudia Giercuszkiewicz, Anna Kasprzycka, Magdalena Skonieczna
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
phenothiazines
diquinothiazines
diazaphenothiazines
anticancer activity
cytotoxicity
apoptosis
Online Access:https://www.mdpi.com/1420-3049/28/7/3248

Internet

https://www.mdpi.com/1420-3049/28/7/3248

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