Modulation of the proteoglycan receptor PTPσ promotes white matter integrity and functional recovery after intracerebral hemorrhage stroke in mice

Modulation of the proteoglycan receptor PTPσ promotes white matter integrity and functional recovery after intracerebral hemorrhage stroke in mice

Abstract Background Intracerebral hemorrhage (ICH) is associated with high morbidity and mortality rates. However, extant investigations have mainly focused on gray matter injury within the primary injury site after ICH rather than on white matter (WM) injury in the brain and spinal cord. This focus...

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Bibliographic Details
Main Authors: Min Yao, Jie Fang, Jiewei Li, Anson Cho Kiu Ng, Jiaxin Liu, Gilberto Ka Kit Leung, Fanglai Song, Jian Zhang, Chunqi Chang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Neuroinflammation
Subjects:
Intracerebral hemorrhage
PTPσ
ISP
Neural circuits integrity
Neuroinflammation
Online Access:https://doi.org/10.1186/s12974-022-02561-4

Internet

https://doi.org/10.1186/s12974-022-02561-4

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