Using whole genome sequence to compare variant callers and breed differences of US sheep

Using whole genome sequence to compare variant callers and breed differences of US sheep

As whole genome sequence (WGS) data sets have become abundant and widely available, so has the need for variant detection and scoring. The aim of this study was to compare the accuracy of commonly used variant calling programs, Freebayes and GATK HaplotypeCaller (GATK-HC), and to use U.S. sheep WGS...

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Bibliographic Details
Main Authors: Morgan R. Stegemiller, Reid R. Redden, David R. Notter, Todd Taylor, J. Bret Taylor, Noelle E. Cockett, Michael P. Heaton, Theodore S. Kalbfleisch, Brenda M. Murdoch
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
sheep
whole genome sequence
freebayes
GATK HaplotypeCaller (HC)
variant callers
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1060882/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.1060882/full

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