Retro-miRs: novel and functional miRNAs originating from mRNA retrotransposition

Retro-miRs: novel and functional miRNAs originating from mRNA retrotransposition

Abstract Background Reverse-transcribed gene copies (retrocopies) have emerged as major sources of evolutionary novelty. MicroRNAs (miRNAs) are small and highly conserved RNA molecules that serve as key post-transcriptional regulators of gene expression. The origin and subsequent evolution of miRNAs...

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Bibliographic Details
Main Authors: Rafael L. V. Mercuri, Helena B. Conceição, Gabriela D. A. Guardia, Gabriel Goldstein, Maria D. Vibranovski, Ludwig C. Hinske, Pedro A. F. Galante
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Mobile DNA
Subjects:
miRNAs
Retrocopies
Gene origination
Gene expression
Cancer
Online Access:https://doi.org/10.1186/s13100-023-00301-w

Internet

https://doi.org/10.1186/s13100-023-00301-w

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