Involvement of KCa3.1 channel activity in immediate perioperative cognitive and neuroinflammatory outcomes

Involvement of KCa3.1 channel activity in immediate perioperative cognitive and neuroinflammatory outcomes

Abstract Background Potassium channels (KCa3.1; Kv1.3; Kir2.1) are necessary for microglial activation, a pivotal requirement for the development of Perioperative Neurocognitive Disorders (PNDs). We previously reported on the role of microglial Kv1.3 for PNDs; the present study sought to determine w...

Full description

Bibliographic Details
Main Authors: Sarah Saxena, Vincent Nuyens, Christopher Rodts, Kristina Jamar, Adelin Albert, Laurence Seidel, Mustapha Cherkaoui-Malki, Jean G. Boogaerts, Heike Wulff, Mervyn Maze, Véronique Kruys, Joseph Vamecq
Format: Article
Language:English
Published: BMC 2023-03-01
Series:BMC Anesthesiology
Subjects:
Neuroinflammation
Surgery
Post-operative cognitive decline
Perioperative neurocognitive disorders
Inflammation
Cognition
Online Access:https://doi.org/10.1186/s12871-023-02030-2

Internet

https://doi.org/10.1186/s12871-023-02030-2

Similar Items