Redox proteomics of PANC-1 cells reveals the significance of HIF-1 signaling protein oxidation in pancreatic ductal adenocarcinoma pathogenesis

Redox proteomics of PANC-1 cells reveals the significance of HIF-1 signaling protein oxidation in pancreatic ductal adenocarcinoma pathogenesis

Abstract Background Protein cysteine oxidation is substantially involved in various biological and pathogenic processes, but its implications in pancreatic cancer development remains poorly understood. Methods and results In this study, we performed a global characterization of protein oxidation tar...

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Bibliographic Details
Main Authors: Chaochao Tan, Lichun Chen, Xiaoyu Guan, Wenyi Huang, Yinhong Feng, Ziyi Li, Ling Wu, Xiangping Huang, Qianhui Ouyang, Sixiang Liu, Ying Huang, Jiliang Hu
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Journal of Translational Medicine
Subjects:
Protein cysteine oxidation
iodoTMT
Redox proteomics
Pancreatic ductal adenocarcinoma
PANC-1
Online Access:https://doi.org/10.1186/s12967-024-05068-z

Internet

https://doi.org/10.1186/s12967-024-05068-z

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