Neutrophil elastase activates the release of extracellular traps from COPD blood monocyte‐derived macrophages
Abstract Neutrophil elastase (NE), a major inflammatory mediator in chronic obstructive pulmonary disease (COPD) airways, impairs macrophage function, contributing to persistence of airway inflammation. We hypothesized that NE activates a novel mechanism of macrophage‐induced inflammation: release o...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-12-01
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Series: | Clinical and Translational Science |
Online Access: | https://doi.org/10.1111/cts.13671 |