Reshaping the tumor microenvironment: The versatility of immunomodulatory drugs in B-cell neoplasms

Immunomodulatory drugs (IMiDs) such as thalidomide, lenalidomide and pomalidomide are antitumor compounds that have direct tumoricidal activity and indirect effects mediated by multiple types of immune cells in the tumor microenvironment (TME). IMiDs have shown remarkable therapeutic efficacy in a s...

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Bibliographic Details
Main Authors: Hao Guo, Jingyi Yang, Haoran Wang, Xingchen Liu, Yanyan Liu, Keshu Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1017990/full