Carrier strategies boost the application of CRISPR/Cas system in gene therapy

Carrier strategies boost the application of CRISPR/Cas system in gene therapy

Abstract Emerging clustered regularly interspaced short palindromic repeat/associated protein (CRISPR/Cas) genome editing technology shows great potential in gene therapy. However, proteins and nucleic acids suffer from enzymatic degradation in the physiological environment and low permeability into...

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Bibliographic Details
Main Authors: Zunkai Xu, Qingnan Wang, Haiping Zhong, Yaoyao Jiang, Xiaoguang Shi, Bo Yuan, Na Yu, Shubiao Zhang, Xiaoyong Yuan, Shutao Guo, Yang Yang
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Exploration
Subjects:
CRISPR
drug delivery
gene therapy
genome editing
nanomaterials
Online Access:https://doi.org/10.1002/EXP.20210081

Internet

https://doi.org/10.1002/EXP.20210081

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