Physiological DNA damage promotes functional endoreplication of mammary gland alveolar cells during lactation
Abstract Lactation insufficiency affects many women worldwide. During lactation, a large portion of mammary gland alveolar cells become polyploid, but how these cells balance the hyperproliferation occurring during normal alveologenesis with terminal differentiation required for lactation is unknown...
| Автори: | , , , , , , , , , |
|---|---|
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Nature Portfolio
2024-04-01
|
| Серія: | Nature Communications |
| Онлайн доступ: | https://doi.org/10.1038/s41467-024-47668-9 |