Synthesis, Molecular Docking, and In Vitro Boron Neutron Capture Therapy Assay of Carboranyl Sinomenine

Synthesis, Molecular Docking, and In Vitro Boron Neutron Capture Therapy Assay of Carboranyl Sinomenine

In comparison with pristine sinomenine and carborane precursors, the calculations of molecular docking with matrix metalloproteinases (MMPs) and methylcarboranyl-<i>n</i>-butyl sinomenine showed improved interactions. Accordingly, methylcarboranyl-<i>n</i>-butyl sinomenine sh...

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Bibliographic Details
Main Authors: Jianghong Cai, Narayan S. Hosmane, Masao Takagaki, Yinghuai Zhu
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Molecules
Subjects:
boron neutron capture synovectomy (BNCS)
boron neutron capture therapy (BNCT)
anti-rheumatoid arthritis
carboranyl sinomenine
molecular docking
Online Access:https://www.mdpi.com/1420-3049/25/20/4697

Internet

https://www.mdpi.com/1420-3049/25/20/4697

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