Co-delivery of sorafenib and metformin from amphiphilic polypeptide-based micelles for colon cancer treatment

Colorectal cancer (CRC) is a common clinical disease with a poor prognosis and a high recurrence rate. Chemotherapy is important to inhibit the post-surgical recurrence of CRC patients. But many limitations restrict the further application of chemotherapy. In this study, sorafenib (Sor) and metformi...

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Bibliographic Details
Main Authors: Xiaohui Zhang, Lanqing Cao, Guangmeng Xu, Hongyu He, Hongyu Zhao, Tongjun Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.1009496/full