HuD regulates SOD1 expression during oxidative stress in differentiated neuroblastoma cells and sporadic ALS motor cortex

HuD regulates SOD1 expression during oxidative stress in differentiated neuroblastoma cells and sporadic ALS motor cortex

The neuronal RNA-binding protein (RBP) HuD plays an important role in brain development, synaptic plasticity and neurodegenerative diseases such as Parkinson's (PD) and Alzheimer's (AD). Bioinformatics analysis of the human SOD1 mRNA 3′ untranslated region (3′UTR) demonstrated the presence...

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Bibliographic Details
Main Authors: Michela Dell'Orco, Valentina Sardone, Amy S. Gardiner, Orietta Pansarasa, Matteo Bordoni, Nora I. Perrone-Bizzozero, Cristina Cereda
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Neurobiology of Disease
Subjects:
Sporadic amyotrophic lateral sclerosis
Oxidative stress
SOD1
ELAVL4/HuD
Motor cortex
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120304861

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http://www.sciencedirect.com/science/article/pii/S0969996120304861

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