Nm23-H1 Regulates Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells via Arf6-Rac1 Signaling Axis

Nm23-H1 Regulates Glucose-Stimulated Insulin Secretion in Pancreatic β-Cells via Arf6-Rac1 Signaling Axis

Background: A growing body of evidence implicates novel roles for nm23-like proteins in the regulation of cellular functions. However, roles of these proteins in islet function and glucose-stimulated insulin secretion (GSIS) remain largely unknown. Methods: siRNA-nm23-H1 and nucleoside diphosphate k...

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Bibliographic Details
Main Authors: Rajakrishnan Veluthakal, David Kaetzel, Anjaneyulu Kowluru
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
nm23-H1
Pancreatic β-cell
Insulin secretion
Rac1 and Arf6
Online Access:http://www.karger.com/Article/FullText/354457

Internet

http://www.karger.com/Article/FullText/354457

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