Long noncoding RNA LINC00930 promotes PFKFB3-mediated tumor glycolysis and cell proliferation in nasopharyngeal carcinoma

Long noncoding RNA LINC00930 promotes PFKFB3-mediated tumor glycolysis and cell proliferation in nasopharyngeal carcinoma

Abstract Background Metabolic reprogramming is a hallmark of cancer. However, the roles of long noncoding RNAs (lncRNAs) in cancer metabolism, especially glucose metabolism remain largely unknown. Results In this study, we identified and functionally characterized a novel metabolism-related lncRNA,...

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Bibliographic Details
Main Authors: Baoyu He, Hongli Pan, Fengque Zheng, Saiqiong Chen, Qingli Bie, Jinghe Cao, Rou Zhao, Jing Liang, Li Wei, Jianchao Zeng, Hui Li, Xing Cui, Yixuan Ding, Wei Chao, Tiantian Xiang, Yuhe Cheng, Gui Qiu, Shishun Huang, Libo Tang, Jiansheng Chang, Delan Luo, Jie Yang, Bin Zhang
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
LINC00930
RBBP5/GCN5
PFKFB3
Glycolysis
Nasopharyngeal carcinoma
Online Access:https://doi.org/10.1186/s13046-022-02282-9

Internet

https://doi.org/10.1186/s13046-022-02282-9

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