Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo

Redox phospholipidomics discovers pro-ferroptotic death signals in A375 melanoma cells in vitro and in vivo

Growing cancer cells effectively evade most programs of regulated cell death, particularly apoptosis. This necessitates a search for alternative therapeutic modalities to cause cancer cell's demise, among them – ferroptosis. One of the obstacles to using pro-ferroptotic agents to treat cancer i...

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Bibliographic Details
Main Authors: Yulia Y. Tyurina, Alexandr A. Kapralov, Vladimir A. Tyurin, Galina Shurin, Andrew A. Amoscato, Dhivyaa Rajasundaram, Hua Tian, Yuri L. Bunimovich, Yulia Nefedova, William G. Herrick, Ralph E. Parchment, James H. Doroshow, Hulya Bayir, Apurva K. Srivastava, Valerian E. Kagan
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Redox Biology
Subjects:
Ferroptosis
Redox lipidomics
Hydroperoxy-phosphatidylethanolamine
Biomarkers
A375 melanoma cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723000514

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http://www.sciencedirect.com/science/article/pii/S2213231723000514

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