Optimization and Validation of an In Vitro Standardized Glycogen Phosphorylase Activity Assay

Optimization and Validation of an In Vitro Standardized Glycogen Phosphorylase Activity Assay

Glycogen phosphorylase (GP) is a key enzyme in the glycogenolysis pathway and a potential therapeutic target in the management of type 2 diabetes. It catalyzes a reversible reaction: the release of the terminal glucosyl residue from glycogen as glucose 1-phosphate; or the transfer of glucose from gl...

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Bibliographic Details
Main Authors: Sónia Rocha, Mariana Lucas, Alberto N. Araújo, M. Luísa Corvo, Eduarda Fernandes, Marisa Freitas
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
glycogen phosphorylase
optimization
enzyme activity
type 2 diabetes
Online Access:https://www.mdpi.com/1420-3049/26/15/4635

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https://www.mdpi.com/1420-3049/26/15/4635

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