Bioisosteric Replacement as a Tool in Anti-HIV Drug Design

Bioisosteric replacement is a powerful tool for modulating the drug-like properties, toxicity, and chemical space of experimental therapeutics. In this review, we focus on selected cases where bioisosteric replacement and scaffold hopping have been used in the development of new anti-HIV-1 therapeut...

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Detalles Bibliográficos
Autores principales: Alexej Dick, Simon Cocklin
Formato: Artículo
Lenguaje:English
Publicado: MDPI AG 2020-02-01
Colección:Pharmaceuticals
Materias:
Acceso en línea:https://www.mdpi.com/1424-8247/13/3/36