NFIL3 Orchestrates the Emergence of Common Helper Innate Lymphoid Cell Precursors

Innate lymphoid cells (ILCs) are a family of effectors that originate from a common innate lymphoid cell progenitor. However, the transcriptional program that sets the identity of the ILC lineage remains elusive. Here, we show that NFIL3 is a critical regulator of the common helper-like innate lymph...

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Autori principali: Wei Xu, Rita G. Domingues, Diogo Fonseca-Pereira, Manuela Ferreira, Hélder Ribeiro, Silvia Lopez-Lastra, Yasutaka Motomura, Lara Moreira-Santos, Franck Bihl, Véronique Braud, Barbara Kee, Hugh Brady, Mark C. Coles, Christian Vosshenrich, Masato Kubo, James P. Di Santo, Henrique Veiga-Fernandes
Natura: Articolo
Lingua:English
Pubblicazione: Elsevier 2015-03-01
Serie:Cell Reports
Accesso online:http://www.sciencedirect.com/science/article/pii/S221112471500234X