Quantifying Next Generation Sequencing Sample Pre-Processing Bias in HIV-1 Complete Genome Sequencing

Genetic analyses play a central role in infectious disease research. Massively parallelized “mechanical cloning” and sequencing technologies were quickly adopted by HIV researchers in order to broaden the understanding of the clinical importance of minor drug-resistant variants. These efforts have,...

Full description

Bibliographic Details
Main Authors: Bram Vrancken, Nídia Sequeira Trovão, Guy Baele, Eric van Wijngaerden, Anne-Mieke Vandamme, Kristel van Laethem, Philippe Lemey
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Viruses
Subjects:
Online Access:http://www.mdpi.com/1999-4915/8/1/12