Sofosbuvir-based direct-acting antivirals and changes in cholesterol and low density lipoprotein-cholesterol

Abstract Worsened lipid profiles were observed in chronic hepatitis C (CHC) patients during direct-acting antivirals (DAAs) treatment, among which combination drugs confounded the effect of individual ingredient on lipid. Tenofovir alafenamide (TAF) also worsened lipid profiles in HIV patients. Stru...

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Bibliographic Details
Main Authors: Yi-Kai Wang, Ying-Wen Wang, Chia-Ling Lu, Yi-Hsiang Huang, Ming-Chih Hou, Yuh-Lih Chang, Wei-Ping Lee, Keng-Hsin Lan
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13657-5