Transcribed Ultraconserved Regions: New regulators in cancer signaling and potential biomarkers
Abstract The ultraconserved regions (UCRs) are 481 genomic elements, longer than 200 bp, 100% conserved in human, mouse, and rat genomes. Usually, coding regions are more conserved, but more than 80% of UCRs are either intergenic or intronic, and many of them produce long non-coding RNAs (lncRNAs)....
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Format: | Article |
Language: | English |
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Sociedade Brasileira de Genética
2023-01-01
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Series: | Genetics and Molecular Biology |
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Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572023000300101&tlng=en |