Sepsis and Nosocomial Infection: Patient Characteristics, Mechanisms, and Modulation

Sepsis and Nosocomial Infection: Patient Characteristics, Mechanisms, and Modulation

Sepsis is a leading cause of death worldwide. After initial trials modulating the hyperinflammatory phase of sepsis failed, generations of researchers have focused on evaluating hypo-inflammatory immune phenotypes. The main goal has been to develop prognostic biomarkers and therapies to reduce organ...

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Bibliographic Details
Main Authors: Scott J. Denstaedt, Benjamin H. Singer, Theodore J. Standiford
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
sepsis
compensatory anti-inflammatory response
priming
nosocomial infection
immunosuppression
SIRS
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02446/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02446/full

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