Using Optimal F-Measure and Random Resampling in Gene Ontology Enrichment Calculations

Using Optimal F-Measure and Random Resampling in Gene Ontology Enrichment Calculations

Background: A central question in bioinformatics is how to minimize arbitrariness and bias in analysis of patterns of enrichment in data. A prime example of such a question is enrichment of gene ontology (GO) classes in lists of genes. Our paper deals with two issues within this larger question. One...

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Bibliographic Details
Main Authors: Weihao Ge, Zeeshan Fazal, Eric Jakobsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Applied Mathematics and Statistics
Subjects:
gene ontology
MCC
resampling
F-measure
false discovery rate
microarray data analysis
Online Access:https://www.frontiersin.org/article/10.3389/fams.2019.00020/full

Internet

https://www.frontiersin.org/article/10.3389/fams.2019.00020/full

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