Neurogenic effects of fingolimod in hippocampus, affecting fear memory.

Fingolimod (FTY720; Gilenya™,Novartis Pharma AG) is a recently developed Sphingosine-1-Phosphate (S1P) analogue, orally administered as a new therapeutic agent in Multiple Sclerosis (MS) (Brinkmann V. et al. 2010). S1P receptors (S1PRs) are expressed in various sites in the CNS including the subven...

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Автори: Paschalis Efstathopoulos, Kyriaki Sidiropoulou
Формат: Стаття
Мова:English
Опубліковано: Frontiers Media S.A. 2014-05-01
Серія:Frontiers in Systems Neuroscience
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Онлайн доступ:http://journal.frontiersin.org/Journal/10.3389/conf.fnsys.2014.05.00002/full