Kidney injury in response to crystallization of calcium oxalate leads to rearrangement of the intrarenal T cell receptor delta immune repertoire

Kidney injury in response to crystallization of calcium oxalate leads to rearrangement of the intrarenal T cell receptor delta immune repertoire

Abstract Background Calcium oxalate (CaOx), the major constituent of most kidney stones, induces inflammatory infiltration and injures renal tubular cells. However, the role of γδT cells in CaOx-mediated kidney injury remains unclear. Therefore, this study investigated the distribution of intrarenal...

Full description

Bibliographic Details
Main Authors: Chao Zhu, Qing Liang, Yaqun Liu, Deliang Kong, Jie Zhang, Hu Wang, Kejia Wang, Zhiyong Guo
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Journal of Translational Medicine
Subjects:
T cell receptor
Immune repertoire
γδT cell
Calcium oxalate
Kidney stone
Online Access:http://link.springer.com/article/10.1186/s12967-019-2022-0

Internet

http://link.springer.com/article/10.1186/s12967-019-2022-0

Similar Items