Ct-OATP1B3 promotes high-grade serous ovarian cancer metastasis by regulation of fatty acid beta-oxidation and oxidative phosphorylation

Abstract High-grade serous ovarian cancer (HGSOC) is the most lethal gynecologic malignancy mainly due to its extensive metastasis. Cancer-type organic anion transporting polypeptide 1B3 (Ct-OATP1B3), a newly discovered splice variant of solute carrier organic anion transporter family member 1B3 (SL...

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Bibliographic Details
Main Authors: Yutang Huang, Yan Du, Yujie Zheng, Chunjie Wen, Hecun Zou, Jiafeng Huang, Honghao Zhou, Hongbo Zhao, Lanxiang Wu
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05014-1