Development and Validation of a Method of Liquid Chromatography Coupled with Tandem Mass Spectrometry for Quantification of ST-246 (Tecovirimat) in Human Plasma

Development and Validation of a Method of Liquid Chromatography Coupled with Tandem Mass Spectrometry for Quantification of ST-246 (Tecovirimat) in Human Plasma

The aim of this work was to develop and validate a sensitive and robust method of liquid chromatography coupled with tandem mass spectrometry to quantitate ST-246 (tecovirimat) in plasma using an internal standard (2-hydroxy-N-{3,5-dioxo-4-azatetracyclo [5.3.2.02.6.08.10]dodec-11-en-4-yl}-5-methylbe...

Full description

Bibliographic Details
Main Authors: Galina A. Oleinik, Vladimir V. Koval, Svetlana V. Usova, Larisa N. Shishkina, Alexander A. Chernonosov
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Molecules
Subjects:
MRM
LC-MS/MS
tecovirimat
ST-246
NIOCH-14
plasma
Online Access:https://www.mdpi.com/1420-3049/27/11/3577

Internet

https://www.mdpi.com/1420-3049/27/11/3577

Similar Items