Morphine and high-fat diet differentially alter the gut microbiota composition and metabolic function in lean versus obese mice

Abstract There are known associations between opioids, obesity, and the gut microbiome, but the molecular connection/mediation of these relationships is not understood. To better clarify the interplay of physiological, genetic, and microbial factors, this study investigated the microbiome and host i...

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Bibliographic Details
Main Authors: J. Alfredo Blakeley-Ruiz, Carlee S. McClintock, Him K. Shrestha, Suresh Poudel, Zamin K. Yang, Richard J. Giannone, James J. Choo, Mircea Podar, Helen A. Baghdoyan, Ralph Lydic, Robert L. Hettich
Format: Article
Language:English
Published: Oxford University Press 2022-08-01
Series:ISME Communications
Online Access:https://doi.org/10.1038/s43705-022-00131-6