The Chromatin Structure at the <i>MECP2</i> Gene and In Silico Prediction of Potential Coding and Non-Coding <i>MECP2</i> Splice Variants

The Chromatin Structure at the <i>MECP2</i> Gene and In Silico Prediction of Potential Coding and Non-Coding <i>MECP2</i> Splice Variants

Methyl CpG binding protein 2 (MeCP2) is an epigenetic reader that binds to methylated CpG dinucleotides and regulates gene transcription. <i>Mecp2</i>/<i>MECP2</i> gene has 4 exons, encoding for protein isoforms MeCP2E1 and MeCP2E2. MeCP2 plays key roles in neurodevelopment,...

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Bibliographic Details
Main Authors: Danilo Shevkoplyas, Yen My Vuu, James R. Davie, Mojgan Rastegar
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:International Journal of Molecular Sciences
Subjects:
epigenetics
MeCP2 isoforms
alternative splicing
genomics
RTT
UCSC
Online Access:https://www.mdpi.com/1422-0067/23/24/15643

Internet

https://www.mdpi.com/1422-0067/23/24/15643

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