Altered DNA methylome profiles of blood leukocytes in Chinese patients with mild cognitive impairment and Alzheimer’s disease

Objective: DNA methylation plays a potential role in the pathogenesis of Alzheimer’s disease (AD). However, little is known about the global changes of blood leukocyte DNA methylome profiles from Chinese patients with mild cognitive impairment (MCI) and with AD, or the specific DNA methylation-based...

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Bibliographic Details
Main Authors: Shaochang Wu, Fan Yang, Shan Chao, Bo Wang, Wuqian Wang, He Li, Limei Yu, Lin He, Xingwang Li, Liya Sun, Shengying Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1175864/full