Synergistic Microbicidal Effect of AUR and PEITC Against Staphylococcus aureus Skin Infection

Synergistic Microbicidal Effect of AUR and PEITC Against Staphylococcus aureus Skin Infection

Given the increasing prevalence of Staphylococcus aureus antibiotic resistance, there is an urgent need to repurpose approved drugs with known pharmacology and toxicology as an alternative therapeutic strategy. We have reported that the sustained monotherapy of auranofin (AUR) inevitably resulted in...

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Bibliographic Details
Main Authors: Haoran Chen, Ning Yang, Liang Yu, Jiajia Li, Hui Zhang, Yahong Zheng, Mengran Xu, Yanyan Liu, Yi Yang, Jiabin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
auranofin (AUR)
phenethyl isothiocyanate (PEITC)
Staphylococcus aureus
thioredoxin reductase (TrxR)
reactive oxygen species (ROS)
skin infections
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.927289/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.927289/full

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