HER2 expression in gastrointestinal tumor. A focus on diagnostic algorithm of HER2 status from gastric to intestinal cancer

Human epidermal growth factor receptor 2 (HER2) is a transmembrane growth factor receptor with tyrosine kinase activity regulating cell growth and survival. HER2 amplification is responsible for protein overexpression with a negative impact on prognosis, but HER2-overexpressing patients could be tre...

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Bibliographic Details
Main Authors: I. Panarese, A. Ronchi, G. Toni, R. Costanzo, G. Casaretta, R. Giannatiempo, R. Sabetta, R. Franco, F. Zito Marino
Format: Article
Language:English
Published: Verduci Editore 2019-03-01
Series:World Cancer Research Journal
Subjects:
Online Access:https://www.wcrj.net/wp-content/uploads/sites/5/2019/03/e1230-HER2-expression-in-gastrointestinal-tumor.-A-focus-on-diagnostic-algorithm-of-HER2-status-from-gastric-to-intestinal-cancer.pdf