Could Local Application of Hypoxia Inducible Factor 1-α Enhancer Deferoxamine Be Promising for Preventing of Medication-Related Osteonecrosis of the Jaw?

Could Local Application of Hypoxia Inducible Factor 1-α Enhancer Deferoxamine Be Promising for Preventing of Medication-Related Osteonecrosis of the Jaw?

This experimental study investigates the prophylactic effect of deferoxamine (DFO) on medication-related osteonecrosis of the jaw (MRONJ). Thirty-six female Sprague Dawley rats received zoledronic acid (ZA) for eight weeks to create an osteonecrosis model. DFO was locally applied into the extraction...

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Bibliographic Details
Main Authors: Gül Merve Yalcin-Ülker, Murat Günbatan, Gonca Duygu, Merva Soluk-Tekkesin, Ceyda Özcakir-Tomruk
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biomedicines
Subjects:
bisphosphonate
deferoxamine
hypoxia-inducible factor 1-alpha
medication-related osteonecrosis of the jaw
tooth extraction
Online Access:https://www.mdpi.com/2227-9059/11/3/758

Internet

https://www.mdpi.com/2227-9059/11/3/758

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