Anti-Inflammatory Effects of Allocryptopine via the Target on the CX3CL1–CX3CR1 axis/GNB5/AKT/NF-κB/Apoptosis in Dextran Sulfate-Induced Mice

Anti-Inflammatory Effects of Allocryptopine via the Target on the CX3CL1–CX3CR1 axis/GNB5/AKT/NF-κB/Apoptosis in Dextran Sulfate-Induced Mice

Allocryptopine (ALL) is an isoquinoline alkaloid extracted from <i>Macleaya cordata</i><b>(Willd). R. Br.</b>, which has been claimed to have anti-inflammatory and neuroprotection properties. However, the mechanism by which ALL ameliorates inflammatory bowel disease (IBD) rem...

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Bibliographic Details
Main Authors: Yang Yang, Tingyu Ding, Gang Xiao, Jialu Huang, Dan Luo, Meishan Yue, Yue Su, Sujuan Jiang, Jianguo Zeng, Yisong Liu
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Biomedicines
Subjects:
allocryptopine
inflammatory bowel disease
chemokine signaling pathway
apoptosis
CX3CL1–CX3CR1 axis
central nervous system
Online Access:https://www.mdpi.com/2227-9059/11/2/464

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https://www.mdpi.com/2227-9059/11/2/464

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