Exploring the Comprehensive Kozak Sequence Landscape for AAV Production in Sf9 System

The widespread successful use of recombinant Adeno-associated virus (rAAV) in gene therapy has driven the demand for scale-up manufacturing methods of vectors with optimized yield and transduction efficiency. The Baculovirus/Sf9 system is a promising platform for high yield production; however, a ma...

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Bibliographic Details
Main Authors: Oleksandr Kondratov, Sergei Zolotukhin
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/10/1983