Myristic acid as a checkpoint to regulate STING-dependent autophagy and interferon responses by promoting N-myristoylation

Stimulator of interferon gene (STING) plays critical roles in the host response to infection and in the production of interferon. Here the authors suggests myristic acid is involved in the homeostatic balancing of STING dependent autophagy and the interferon response.

Bibliographic Details
Main Authors: Mutian Jia, Yuanyuan Wang, Jie Wang, Danhui Qin, Mengge Wang, Li Chai, Yue Fu, Chunyuan Zhao, Chengjiang Gao, Jihui Jia, Wei Zhao
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-36332-3