Aprepitant, an antiemetic agent, interferes with metal ion homeostasis of Candida auris and displays potent synergistic interactions with azole drugs

With the rapid increase in the frequency of azole-resistant species, combination therapy appears to be a promising tool to augment the antifungal activity of azole drugs against resistant Candida species. Here, we report the effect of aprepitant, an antiemetic agent, on the antifungal activities of...

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Bibliographic Details
Main Authors: Hassan E. Eldesouky, Nadia A. Lanman, Tony R. Hazbun, Mohamed N. Seleem
Format: Article
Language:English
Published: Taylor & Francis Group 2020-12-01
Series:Virulence
Subjects:
Online Access:http://dx.doi.org/10.1080/21505594.2020.1838741