Methionine Sulfoxide Reductases Suppress the Formation of the [<i>PSI</i><sup>+</sup>] Prion and Protein Aggregation in Yeast

Prions are self-propagating, misfolded forms of proteins associated with various neurodegenerative diseases in mammals and heritable traits in yeast. How prions form spontaneously into infectious amyloid-like structures without underlying genetic changes is poorly understood. Previous studies have s...

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Bibliographic Details
Main Authors: Jana Schepers, Zorana Carter, Paraskevi Kritsiligkou, Chris M. Grant
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/12/2/401