Renin–Angiotensin System Antagonism Protects the Diabetic Heart from Ischemia/Reperfusion Injury in Variable Hyperglycemia Duration Settings by a Glucose Transporter Type 4-Mediated Pathway

Renin–Angiotensin System Antagonism Protects the Diabetic Heart from Ischemia/Reperfusion Injury in Variable Hyperglycemia Duration Settings by a Glucose Transporter Type 4-Mediated Pathway

Background: Diabetes mellitus (DM) is a risk factor for cardiovascular diseases, specifically, the ischemic heart diseases (IHD). The renin–angiotensin system (RAS) affects the heart directly and indirectly. However, its role in the protection of the heart against I/R injury is not completely unders...

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Bibliographic Details
Main Authors: Aisha Al-Kouh, Fawzi Babiker, Maie Al-Bader
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceuticals
Subjects:
ischemia reperfusion
RAS
captopril
losartan
diabetes mellitus
hyperglycemia
Online Access:https://www.mdpi.com/1424-8247/16/2/238

Internet

https://www.mdpi.com/1424-8247/16/2/238

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