Targeting B7-H3—A Novel Strategy for the Design of Anticancer Agents for Extracranial Pediatric Solid Tumors Treatment

Targeting B7-H3—A Novel Strategy for the Design of Anticancer Agents for Extracranial Pediatric Solid Tumors Treatment

Recent scientific data recognize the B7-H3 checkpoint molecule as a potential target for immunotherapy of pediatric solid tumors (PSTs). B7-H3 is highly expressed in extracranial PSTs such as neuroblastoma, rhabdomyosarcoma, nephroblastoma, osteosarcoma, and Ewing sarcoma, whereas its expression is...

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Bibliographic Details
Main Authors: Petar Rasic, Marija Jeremic, Rada Jeremic, Marija Dusanovic Pjevic, Milica Rasic, Slavisa M. Djuricic, Maja Milickovic, Miroslav Vukadin, Tanja Mijovic, Djordje Savic
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
B7-H3
pediatric solid tumors
anticancer agents
targeted therapy
immunotherapy
Online Access:https://www.mdpi.com/1420-3049/28/8/3356

Internet

https://www.mdpi.com/1420-3049/28/8/3356

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